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Updated: Mar 15, 2026

Multimedia Battery for Assessment of Cognitive and Basic Skills in Mathematics BM-PROMA
Published on: August 28, 2021
Specialization of the Right Intraparietal Sulcus for Processing Mathematics During Development
Margot A Schel1, Torkel Klingberg1
1Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.
The right anterior intraparietal sulcus (IPS) initially supports both math and spatial memory in children. This brain region later specializes for mathematical abilities, not spatial memory, in adults.
Area of Science:
- Neuroscience
- Cognitive Development
- Developmental Psychology
Background:
- Mathematical ability and working memory involve overlapping brain regions, particularly the intraparietal sulcus (IPS).
- Previous studies using group averages obscure individual anatomical specificity for cognitive functions.
- Understanding the precise localization of mathematical functions requires analyzing individual brain variations.
Purpose of the Study:
- To investigate the functional anatomy of the intraparietal cortex using individual analyses.
- To determine how structural connectivity of IPS subregions relates to cognitive functions like mathematics and working memory.
- To explore developmental changes in the specialization of IPS regions.
Main Methods:
- Individual analysis of intraparietal sulcus (IPS) subregions based on structural connectivity to frontal, parietal, and occipital cortices.
- Cortical thickness analysis to correlate brain structure with cognitive performance.
- Examination of mathematical ability and visuospatial working memory in children, adolescents, and adults.
Main Results:
- The right anterior IPS, connected to the frontal lobe, is associated with both visuospatial working memory and mathematical abilities in 6-year-old children.
- This specific right anterior IPS region demonstrates developmental specialization, becoming uniquely related to mathematics in adolescents and adults.
- Visuospatial working memory function in older individuals is not associated with this specialized mathematical region.
Conclusions:
- The right anterior IPS undergoes interactive specialization during development, transitioning from a general spatial role to a mathematics-specific function.
- This developmental trajectory highlights how environmental interactions and inter-regional communication shape cognitive specializations.
- Individual-based analysis is crucial for accurately mapping cognitive functions to specific brain regions.
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