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Updated: Mar 15, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Secondary hemochromatosis as a result of acute transfusion-induced iron overload in a burn patient
Michael Amatto1, Hernish Acharya2
1University of Alberta, 8440 112 Street, Edmonton, AB T6G 2B7 Canada.
Background:
Red blood cell transfusions are critical in burn management. The subsequent iron overload that can occur from this treatment can lead to secondary hemochromatosis with multi-organ damage.
Case Presentation:
While well recognized in patients receiving chronic transfusions, we present a case outlining the acute development of hemochromatosis secondary to multiple transfusions in a burn patient.
Conclusions:
Simple screening laboratory measures and treatment options exist which may significantly reduce morbidity; thus, we believe awareness of secondary hemochromatosis in those treating burn patients is critical.
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