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Cow's Milk Protein Allergy

Grace Mousan1, Deepak Kamat2

  • 1Children's Hospital of Michigan, Detroit, MI, USA gmousanyazigi@gmail.com.

Clinical Pediatrics
|September 2, 2016
PubMed

Insights

Cow

Area of Science:

  • Pediatrics
  • Allergy Immunology
  • Clinical Nutrition

Background:

  • Cow's milk protein allergy (CMPA) affects 2-7.5% of infants.
  • Symptoms manifest in both formula-fed and breastfed infants.
  • Accurate diagnosis is crucial to prevent under- or overdiagnosis.

Purpose of the Study:

  • To review the definition, epidemiology, risk factors, pathogenesis, clinical presentation, evaluation, management, and prognosis of CMPA.
  • To provide an overview of formula options for CMPA treatment.

Main Methods:

  • Literature review of CMPA.
  • Analysis of clinical manifestations, diagnostic approaches, and treatment strategies.

Main Results:

  • CMPA is categorized into IgE- or non-IgE-mediated reactions.
  • Gastrointestinal, skin, and respiratory systems are most commonly affected.
  • Management involves CMP avoidance and appropriate formula selection.

Conclusions:

  • CMPA requires careful diagnosis and management.
  • Dietary modification and specialized formulas are key treatment components.
  • Understanding CMPA's multifaceted nature is essential for pediatric care.

Keywords:
Allergic colitisallergyamino-acid based formulabreast-feedingcow’s milkelimination dietextensively hydrolyzed formulaformula feedingoral challengeprotein

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