Annular erythema in identical twins.

Area of Science:

• Dermatology
• Genetics
• Clinical Medicine

Background:

• Superficial gyrate erythema is a descriptive term for various annular skin conditions.
• Erythema annulare centrifugum (EAC) is a specific type of reactive erythema.
• The etiology of EAC is often idiopathic or associated with underlying conditions.

Observation:

• A rare case of superficial gyrate erythema was observed in identical twins.
• The clinical presentation in both twins was indistinguishable from classic erythema annulare centrifugum.
• This concordance suggests a potential genetic predisposition or familial link.

Findings:

• The identical presentation in twins supports a hereditary component in certain cases of EAC.
• The findings challenge the classification of familial annular erythema as a distinct entity.
• A familial cause should be considered within the spectrum of EAC.

Implications:

• This case broadens the understanding of EAC's etiology, including genetic factors.
• It may lead to revised diagnostic criteria for erythema annulare centrifugum.
• Further research into familial patterns of EAC is warranted.