Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach.

Area of Science:

• Ophthalmology
• Medical Imaging

Background:

• Multifocal choroiditis (MFC) can cause visual impairment due to inflammatory lesions and choroidal neovascularization (CNV).
• Accurate differentiation between inflammation and CNV is crucial for effective treatment strategies in MFC patients.

Observation:

• A case study investigated the use of optical coherence tomography angiography (OCT-A) in a patient with suspected macular CNV reactivation due to MFC.
• Standard angiographies and structural OCT were compared with OCT-A findings.

Findings:

• OCT-A revealed no decorrelation signal indicative of CNV over or between the retinal pigment epithelium (RPE) and Bruch's membrane.
• This suggests OCT-A can distinguish active CNV from inflammatory changes in MFC.

Implications:

• OCT-A demonstrates significant clinical utility in characterizing and differentiating inflammatory lesions from CNV in MFC.
• This advanced imaging modality can guide therapeutic decisions, potentially preventing vision loss in patients with complex retinal diseases.