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PGD: a pangolin genome hub for the research community
Tze King Tan1, Ka Yun Tan2, Ranjeev Hari1
1Genome Informatics Research Laboratory, Centre for Research in Biotechnology for Agriculture (CEBAR), High Impact Research Building, University of Malaya, 50603 Kuala Lumpur, Malaysia Department of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Database : the Journal of Biological Databases and Curation
|September 13, 2016
Summary
Researchers sequenced the genomes of two endangered pangolin species, providing essential data for conservation and evolutionary studies. A new Pangolin Genome Database (PGD) offers genomic resources and analysis tools for the scientific community.
Area of Science:
- Genomics
- Mammalian Biology
- Conservation Science
Background:
- Pangolins (order Pholidota) are unique scaly mammals facing critical endangerment.
- Understanding pangolin genomics is crucial for their conservation and advancing mammalian evolutionary knowledge.
Purpose of the Study:
- To sequence and analyze the genomes of two critically endangered Asian pangolin species.
- To establish a centralized resource, the Pangolin Genome Database (PGD), for pangolin genomic and transcriptomic data.
- To provide valuable analysis tools for researchers studying pangolins and mammalian evolution.
Main Methods:
- Whole-genome sequencing of Malayan pangolin (Manis javanica) and Chinese pangolin (Manis pentadactyla).
- Bioinformatic analysis of genomic and transcriptomic data.
- Development and curation of the Pangolin Genome Database (PGD).
Main Results:
- Complete genome sequences for two endangered Asian pangolin species are now available.
- The Pangolin Genome Database (PGD) is established, hosting diverse genomic data, including gene sequences, functional information, and expression data.
- PGD includes annotations for pseudogenes, genomic variations, and organ-specific expression.
Conclusions:
- The generated genome sequences and the PGD are invaluable resources for pangolin conservation efforts.
- This initiative will significantly advance research in pangolin biology, evolution, and comparative genomics.
- The PGD will be continuously updated, fostering a collaborative global research effort in pangolin studies.
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