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Bacterial Uropathogens Causing Urinary Tract Infection and Their Resistance Patterns Among Children in Turkey
Yunus Yilmaz1, Zuhal Tekkanat Tazegun2, Emsal Aydin3
1Department of Pediatrics, Kafkas University Training and Research Hospital, Kars, Turkey.
Insights
This study identified common bacterial causes of urinary tract infections (UTIs) in children and their antibiotic resistance patterns. Escherichia coli was the most frequent pathogen, highlighting the need for updated antimicrobial policies.
Area of Science:
- Pediatric infectious diseases
- Clinical microbiology
- Antimicrobial resistance
Background:
- Urinary tract infections (UTIs) are a significant health concern in pediatric populations.
- Understanding causative agents and resistance is crucial for effective treatment.
Purpose of the Study:
- To determine the most common bacterial uropathogens in children with UTIs.
- To assess the antibiotic susceptibility and resistance patterns of these pathogens.
Main Methods:
- Analysis of 7,365 pediatric urine samples collected between January 2012 and May 2014.
- Standard microbiological methods for bacterial isolation and identification.
- Disk diffusion method for antibiotic susceptibility testing, following CLSI guidelines.
Main Results:
- Bacterial growth was observed in 18.5% of samples.
- Escherichia coli was the predominant uropathogen (68.5%), followed by Proteus spp. (13.3%) and Staphylococcus spp. (6.2%).
- UTIs were more common in females over two years of age.
Conclusions:
- E. coli is the primary cause of pediatric UTIs in the studied region.
- Knowledge of local resistance patterns is essential for guiding antimicrobial therapy and infection control strategies.
Background:
Urinary tract infection (UTI) is a common problem in infants and children, as well as adults.
Objectives:
The aim of this study was to assess the most common bacterial uropathogens, their susceptibility, and resistance to antibiotics in children with UTI.
Materials And Methods:
This study included 7,365 urine samples sent from various departments to the Kars state hospital microbiology laboratory between January 2012 and May 2014. Bacterial isolation from clinical samples was made using standard microbiological methods. Antibiotic susceptibilities were determined by disk diffusion, according to CLSI recommendations.
Results:
Bacterial growth was obtained in 1,373 samples (18.5%). The percentage distributions of the isolates were as follows: Escherichia coli, 940 (68.5%); Proteus spp, 183 (13.3%); Staphylococcus spp, 85 (6.2%); Enterococcus spp, 65 (4.7%); Klebsiella, 62 (4.5%); Pseudomonas aeruginosa, 21 (1.5%); and other Gram-negative bacteria and Gram-positive bacteria, 17 (1.2%). UTIs were more prevalent, after two years of age, among females than males (P < 0.001).
Conclusions:
The identification of the most common microorganisms causing infectious diseases and regional resistance patterns is important in order to determine the antimicrobial policies and infection control guidelines of hospitals.
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