Disappearance of Idiopathic Outflow Tract Premature Ventricular Contractions After Catheter Ablation of Overt

Tamas Szili Torok1, Lennart J DE Vries1, Emin E Özcan2

  • 1Department of Cardiology, Electrophysiology, Erasmus Medical Center, Rotterdam, The Netherlands.

Abstract

Insights

Idiopathic premature ventricular contractions (PVCs) from the outflow tracts may be linked to accessory pathways (APs). Ablating APs often resolves these PVCs, suggesting a shared origin for both conditions.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Arrhythmias

Background:

  • Idiopathic premature ventricular contractions (PVCs) originating from the outflow tracts (OTs) have multiple proposed mechanisms.
  • Coexistence with atrioventricular nodal reentrant tachycardias and association with successful ablation sites suggest a common link.

Purpose of the Study:

  • To highlight a unique association between accessory pathways (APs) and idiopathic PVCs originating from the OTs.
  • To investigate the effect of AP ablation on these PVCs.

Main Methods:

  • A case series of 6 patients with pre-excitation and outflow tract (OT) PVCs identified.
  • Analysis of 12-lead surface ECGs and outcomes after accessory pathway ablation.

Main Results:

  • Six cases showed pre-excitation and PVCs, mostly from the right ventricular outflow tract (RVOT).
  • Catheter ablation of the accessory pathway resolved PVCs in 5 out of 6 cases, with ablation sites remote from the OTs.
  • PVC occurrence was closely associated with the presence of pre-excitation.

Conclusions:

  • The coexistence of pre-excitation and OT PVCs suggests a common mechanism for their genesis.
  • Successful AP ablation leading to PVC resolution supports a shared pathway in arrhythmia development.

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