Morphometric Analysis of Peripapillary Thickness in Hypertensives and Normotensives using Optical Coherence
Krishna Rao Addoor1, Sulatha V Bhandary2, Lavanya G Rao3
1Professor and Head, Department of Ophthalmology, Kasturba Medical College , Manipal, Karnataka, India .
Introduction:
Hypotension following antihypertensive treatment is associated with retinal nerve fibre loss. There are studies that have reported the changes in RNFL in hypertensives.
Aim:
To compare the Retinal Nerve Fibre Layer (RNFL) thickness using Optical Coherence Tomography (OCT) in hypertensive and normotensive individuals.
Materials And Methods:
The cross-sectional study was conducted from October 2012 to September 2014 to compare the RNFL thickness using SD OCT in hypertensive {no other ocular or systemic co-morbidity, vision better or equal to 6/9 (n=30)} and normotensive (n=30) individuals.
Results:
Statistically significant RNFL loss was detected in hypertensives (98.31 ± 7.01) when compared to the normotensives (102.51 ± 8.72) p=0.001.
Conclusion:
Significant loss of RNFL in hypertensives point towards the altered autoregulation and warrants larger studies to assess the clinical relevance.
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