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Updated: Feb 12, 2026
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A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
Published on: February 2, 2022
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[Urinary lithiasis in renal transplant recipient].
J Branchereau1, R Thuret2, F Kleinclauss3
1Service d'urologie et transplantation rénale, CHU de Nantes, 44000 Nantes, France.
Summary
Urinary lithiasis in kidney transplant recipients is common and often asymptomatic. However, it poses a significant risk due to immunosuppression and the presence of a single functioning kidney, requiring specialized urological care.
Area of Science:
- Nephrology
- Urology
- Transplantation Medicine
Background:
- Urinary lithiasis, or kidney stones, can affect kidney transplant recipients.
- The epidemiology and management of stones in allografts are critical concerns.
Purpose of the Study:
- To review the epidemiology and characteristics of urinary lithiasis in kidney allografts.
- To outline the management strategies for kidney allograft stones.
Main Methods:
- Systematic literature review of Medline and Embase databases.
- Inclusion of studies from the last 10 years, focusing on urinary lithiasis and kidney transplantation.
- Analysis of 37 relevant articles, including prospective, retrospective, and review studies.
Main Results:
- Urinary lithiasis frequency in renal transplant recipients mirrors the general population.
- Stones in allografts are often asymptomatic due to renal denervation but pose risks.
- Diagnosis is typically incidental; management aligns with general population protocols.
Conclusions:
- Urolithiasis in kidney transplant recipients is a serious condition requiring expert urological management.
- The immunosuppressed state and single functioning kidney heighten the risk.
- Prompt and specialized care is essential for optimal outcomes.
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