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Pediatric Contact Dermatitis Registry Inaugural Case Data.

Alina Goldenberg1, Nico Mousdicas, Nanette Silverberg

  • 1From the *Department of Dermatology, University of California San Diego, La Jolla; †Department of Dermatology, Indiana University Health, Indianapolis; ‡Icahn School of Medicine at Mount Sinai, New York, NY; §Department of Dermatology, University of Utah, Salt Lake City; ∥Department of Pediatrics, Eastern Maine Medical Center, Bangor; ¶College of Medicine, The University of Vermont, Burlington; #Department of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL; **Weill Medical College of Cornell University, New York, NY; ††Department of Medicine, State University of New York at Stony Brook, NY; ‡‡Allergy & Immunology Training Program, Winthrop University Hospital, Mineola, NY; §§Department of Dermatology & Cutaneous Surgery, University of Miami, Gables, FL; ∥∥Department of Dermatology and Pediatrics, Emory University School of Medicine, Atlanta, GA; ¶¶Department of Dermatology and Pediatrics, University of Connecticut School of Medicine, Farmington; ##Clinical Dermatology, Northwestern University, Chicago, IL; ***Department of Pediatrics, University of Miami Miller School of Medicine, FL; †††Children's Specialty Group, Department of Pediatrics and Dermatology, Eastern Virginia Medical School, Norfolk; ‡‡‡Department of Dermatology, Yale School of Medicine, New Haven, CT; §§§Department of Dermatology, University of Colorado Denver; ∥∥∥Denver VAMC, CO; ¶¶¶Vanguard Skin Specialists, Colorado Springs; ###Department of Dermatology, University of California San Diego; ****Department of Dermatology, Medical College of Wisconsin, Milwaukee; ††††Asthma and Allergy Care of Delaware, Newark; ‡‡‡‡Department of Dermatology, University of California San Francisco; §§§§The Everett Clinic, Dermatology Department, WA; ∥∥∥∥Physicians Skin Care, PLLC Louisville, KY, ¶¶¶¶DermResearch, PLLC, Louisville, KY and Icahn School of Medicine

Dermatitis : Contact, Atopic, Occupational, Drug
|September 21, 2016
PubMed
Summary
This summary is machine-generated.

Allergic contact dermatitis (ACD) affects many US children, with over half showing positive patch tests. Common culprits include nickel and fragrance mix I, highlighting the need for product reformulation.

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Area of Science:

  • Pediatric dermatology
  • Allergology
  • Epidemiology

Background:

  • Epidemiology of allergic contact dermatitis (ACD) in US children is poorly understood.
  • Diagnostic confirmation via epicutaneous patch testing is crucial for accurate diagnosis.

Purpose of the Study:

  • To quantify patch test results in US children evaluated by healthcare providers.
  • To establish a baseline for pediatric ACD epidemiology.

Main Methods:

  • Retrospective analysis of deidentified patch test data from the Pediatric Contact Dermatitis Registry (2015-2016).
  • Inclusion of children aged 18 years or younger from 34 US states.
  • Data collected from 84 participating providers.

Main Results:

  • 1,142 pediatric cases analyzed.
  • 65% of cases showed at least one positive patch test (PPT).
  • 48% of cases had a relevant positive patch test (RPPT). Common allergens included nickel (22%), fragrance mix I (11%), and cobalt (9.1%).

Conclusions:

  • The US registry validates high pediatric ACD rates.
  • This database is a significant resource for future pediatric ACD research.
  • Collaboration is needed to reduce common allergens in children's products.