Transcatheter aortic valve replacement in unicuspid aortic valve stenosis

Area of Science:

• Cardiovascular medicine
• Interventional cardiology

Background:

• Unicuspid aortic valve (UAV) is a rare congenital anomaly.
• Transcatheter aortic valve replacement (TAVR) is a standard treatment for aortic stenosis.
• TAVR in UAV is not well-described, posing unique implantation challenges.

Observation:

• A challenging case of TAVR in a patient with UAV is presented.
• The implantation involved asymmetric expansion and prosthesis apposition issues.
• An Edwards Sapiens prosthesis was used via a transapical approach.

Findings:

• Successful TAVR implantation in a patient with UAV was achieved.
• The transapical approach facilitated prosthesis placement in this complex anatomy.
• This case demonstrates the feasibility of TAVR in UAV.

Implications:

• This case expands the understanding of TAVR in rare aortic valve anomalies.
• It highlights potential strategies for managing UAV during TAVR.
• Further research is needed to establish TAVR as a viable option for UAV patients.