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The High Blood Pressure-Malaria Protection Hypothesis

Julio Gallego-Delgado1, Thomas Walther2, Ana Rodriguez1

  • 1From the Department of Microbiology, New York University School of Medicine (J.G.-D., A.R.); and Department of Pharmacology and Therapeutics, School of Medicine and School of Pharmacy, University College Cork (UCC), Ireland (T.W.).

Circulation Research
|September 24, 2016
PubMed
Summary

Elevated angiotensin II (Ang II) levels may protect against severe malaria, offering a new explanation for hypertension in malaria-endemic regions. This finding suggests novel therapeutic strategies for cerebral malaria.

Keywords:
angiotensin IIblood pressureepidemiologyhypertensionmalaria

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