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Postprandial gastrin concentrations are higher in female patients with duodenal ulcers
J Calam1, C J Springer, J C Bojarski
1Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
Digestion
|January 1, 1989
Abstract:
We compared plasma gastrin concentrations in male and female patients with duodenal ulcers because a group in Denmark reported a difference, but two groups in the Far East did not. Median basal gastrin was 23 pmol/l in males compared with 43 pmol/l in females. Median peak postprandial gastrin was 71 pmol/l in males, compared with 142 pmol/l in females (p less than 0.03). Elevated gastrin may reflect diminished sensitivity of parietal cells to gastrin in females.