TORS in HPV-Positive Tumors-The New Standard?

Area of Science:

• Oncology
• Surgical Robotics
• Otolaryngology

Background:

• Human papillomavirus (HPV) is a key factor in oropharyngeal squamous cell carcinoma (OPSCC) development.
• Transoral robotic surgery (TORS) has emerged as a significant treatment modality for head and neck squamous cell carcinoma (HNSCC).
• Current TORS systems face limitations, particularly in endolaryngeal procedures, necessitating further technical development.

Purpose of the Study:

• To discuss the implications of tumor site and microenvironment in HPV-associated cancer.
• To evaluate the role and limitations of transoral robotic surgery (TORS) in treating HPV-associated cancers, specifically HNSCC and OPSCC.
• To highlight the need for further technical advancements in TORS for improved patient outcomes.

Main Methods:

• Review of current literature on HPV-associated cancers and TORS.
• Discussion of the technical aspects and limitations of TORS in head and neck surgery.
• Exploration of the potential benefits of new robotic systems, such as the Flex System.

Main Results:

• TORS is increasingly utilized and offers a valuable surgical alternative for HPV-related OPSCC.
• Ongoing development in robotic systems promises to enhance TORS efficacy, reduce patient morbidity, and potentially lower treatment costs.
• Further evaluation of new systems like the Flex System is required.

Conclusions:

• TORS is a valuable surgical option for HPV-related OPSCC, with ongoing technological improvements expected to enhance its benefits.
• Addressing current limitations in visualization and manipulation, especially for endolaryngeal procedures, is crucial for advancing TORS.
• Prospective trials are essential to rigorously assess the advantages and disadvantages of evolving TORS systems in patient care.