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Updated: Mar 14, 2026

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
Published on: December 8, 2010
Tissue oxygenation, perfusion, and position in patients with venous leg ulcers
1Homerton College, Cambridge School of Health Studies.
Abstract:
Inadequate oxygenation impairs the wound healing process, and so ensuring optimal delivery of oxygen to the tissues is likely to be an important issue in promoting the healing of venous leg ulcers. This study used a convenience sample of 31 patients (with an age range of29to86years: mean age59.8years) who were attending vascular clinics on the west coast of the USA. Measurements indicated that control of peripheral circulation and tissue oxygenation may be impaired in people with venous ulcers. Leg elevation, sitting and standing decreased wound perfusion, and so the authors suggest that more research is necessary to investigate these relationships in more detail. 53 references.
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