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Studying the Relation of Postprandial Triglyceride with Coronary Artery Disease (CAD)
Mohammad Manochehri1, Adel Johari Moghadam2
1AJA University of Medical Sciences, Tehran, Iran.
Insights
Postprandial triglyceride levels are significantly higher in coronary artery disease (CAD) patients. Measuring postprandial triglyceride is a more sensitive indicator for CAD risk than fasting triglyceride levels.
Area of Science:
- Cardiology
- Metabolic Syndrome
- Lipid Metabolism
Background:
- Coronary artery disease (CAD) is a leading global cause of mortality.
- Identifying contributing factors to CAD is crucial for prevention and management.
Purpose of the Study:
- To investigate the association between postprandial triglyceride levels and coronary artery disease (CAD).
- To compare the diagnostic value of postprandial versus fasting triglyceride levels in patients with established CAD.
Main Methods:
- An observational case-control study involving 80 male participants.
- Participants were divided into two groups: those with angiographically proven CAD and a healthy control group.
- Fasting serum triglyceride and 4-hour postprandial triglyceride levels were measured and analyzed.
Main Results:
- Both fasting and postprandial triglyceride levels were significantly elevated in patients with CAD (P=0.001).
- Postprandial triglyceride measurement demonstrated higher sensitivity in identifying CAD patients compared to fasting triglyceride levels.
Conclusions:
- Elevated postprandial triglyceride levels are a reliable indicator of coronary artery disease.
- Postprandial triglyceride assessment offers greater reliability than fasting triglyceride levels for patients with CAD.
Background:
Coronary artery disease (CAD) is the most common cause of mortality worldwide and determination of contributing factors is essential.
Aim:
This study was conducted to study the relation of postprandial triglyceride as a risk of coronary artery disease in patients with proven CAD by angiography, referred to 502 Hospital of Army in 2015.
Material And Methods:
This observational study conducted as a case-control and contained 80 male participants referred to 502 Hospital of Army. Half of these participants had proven CAD by angiography test and the other ones were healthy as a control group. Fasting serum triglyceride was evaluated in all participants and postprandial TG was checked 4 hours after a standard meal. Obtained data were analyzed by SPSS ver. 13.
Results:
The results indicated that fasting TG and postprandial TG level were significantly higher in CAD patients (P-value=0.001). It was also shown evaluation of postprandial TG is more sensitive test than fasting TG in case of CAD patients.
Conclusion:
Our obtained results shown, evaluation of high level of postprandial TG is more reliable than fasting TG for patients whom suffer from CAD.
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