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Updated: Mar 14, 2026

CIRCLE-Seq for Interrogation of Off-Target Gene Editing
Published on: November 1, 2024
Visualization analysis of CRISPR/Cas9 gene editing technology studies
Quan-Sheng Du1, Jie Cui2, Chun-Jie Zhang3
1Department of Life Sciences, National Natural Science Foundation of China, Beijing 100085, China.
Abstract:
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system is an adaptive immune defense system that resists the invasion of viruses and plasmids heterologous genetic material in bacteria and archaea. Taking the literature related to gene editing technology of CRISPR/Cas9 from the Web of Science database from 2002 to 2015, we use the software CiteSpaceV to analyze co-cited literature in order to establish the research hotspots and fronts recently in this field by knowledge mapping.
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