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Preserving the adhesion of catechol-conjugated hydrogels by thiourea-quinone coupling
Yang J Xu1, Kongchang Wei2, Pengchao Zhao1
1Division of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, The People's Republic of China. lbian@mae.cuhk.edu.hk and Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong, The People's Republic of China.
Abstract:
Mussel adhesion has inspired the development of catechol-based adhesive polymers. However, conventional strategies require basic pH conditions and lead to the loss of adhesion. To solve the problem, we report the first attempt to use thiourea-functionalized polymers for preserving hydrogel adhesion. We believe that this simple thiourea-quinone coupling chemistry is instrumental to synthetic adhesive materials.
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