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Cyclic Vomiting Syndrome: An Update Illustrated by a Case Report
Ingeborg P M Hermus1, Stacey J B Willems1, Aimée C C F Bogman1
1Department of Psychiatry and Psychology, Division of Child and Adolescent Psychiatry and Psychology, Maastricht University Medical Center, Maastricht, The Netherlands.
Cyclic vomiting syndrome can be debilitating. Antipsychotics like risperidone, combined with amitriptyline, show promise for treating difficult cases of cyclic vomiting syndrome.
Area of Science:
- Neurology
- Pharmacology
Background:
- Cyclic vomiting syndrome (CVS) is a debilitating disorder impacting quality of life.
- Current literature on CVS treatment is limited, particularly regarding antipsychotic use.
Observation:
- A literature search identified limited information on antipsychotics for CVS.
- A case report details a 15-year-old boy with refractory CVS who responded to risperidone and amitriptyline.
Findings:
- Antipsychotics are rarely discussed for their antiemetic properties in CVS literature.
- Chlorpromazine is mentioned, but its mechanism remains unclear.
Implications:
- Antipsychotics, specifically risperidone combined with amitriptyline, may offer a new treatment avenue for refractory CVS.
- Further research is warranted to explore the efficacy and mechanisms of antipsychotics in CVS management.
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