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90Y Digital PET/CT Imaging Following Radioembolization
Chadwick L Wright1, Jun Zhang, Katherine Binzel
1From the *Wright Center of Innovation and Biomedical Imaging, Department of Radiology, and †Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH.
New digital photon counting PET/CT offers superior imaging for Yttrium-90 radioembolization (RE) liver metastases. This advanced technology provides better contrast and biodistribution visualization compared to older methods.
Area of Science:
- Nuclear Medicine
- Radiology
- Oncology
Background:
- Yttrium-90 (Y) radioembolization (RE) is used for liver metastases.
- Conventional photomultiplier detector PET has limitations in imaging Y-90 RE.
- Bremsstrahlung SPECT/CT is an alternative imaging modality.
Observation:
- A 54-year-old man with rectal carcinoma liver metastases underwent Y-90 RE.
- The patient was subsequently imaged using novel solid-state digital photon counting PET/CT (Vereos 64 TOF PET/CT).
- Imaging was performed 26 hours post-RE.
Findings:
- Digital PET/CT demonstrated improved image quality compared to Bremsstrahlung SPECT/CT.
- Enhanced Y-90 to background contrast was observed with digital PET/CT.
- Accurate visualization of Y-90 biodistribution was achieved with the new technology.
Implications:
- Solid-state digital photon counting PET/CT enhances post-Y-90 RE imaging assessment.
- This technology may improve treatment monitoring and patient outcomes.
- Digital PET/CT offers a valuable advancement for Y-90 RE therapy evaluation.
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