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New horizon in platelet function: with special reference to a recently-found molecule, CLEC-2

Yukio Ozaki1, Shogo Tamura2, Katsue Suzuki-Inoue3

  • 1Fuefuki Central Hospital, 47-1 Yokkaichiba, Isawa, Fuefuki, 406-0032 Yamanashi Japan.

Thrombosis Journal
|October 22, 2016
PubMed
Summary

Platelets interact with podoplanin via CLEC-2, crucial for lymphatic/blood vessel separation and megakaryopoiesis. This interaction influences organ development, immunity, and disease, highlighting novel platelet functions.

Keywords:
Beyond hemostasisCLEC-2ImmunityLymphangiogeneisMegakaryopoiesisPlateletsSmooth muscle cellsThrombosis

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