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Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury
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Aortic thrombosis in dogs.

Trevor P E Williams1, Scott Shaw1, Adam Porter1

  • 1VCA Veterinary Referral Associates, Gaithersburg, MD, 20877.

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001)
|October 26, 2016
PubMed
Summary
This summary is machine-generated.

Aortic thrombosis in dogs often stems from hypercoagulable states, with diagnosis challenging due to varied signs. Survival rates are around 50-60%, with chronic cases showing a better prognosis.

Keywords:
anticoagulationantiplateletheparinhypercoagulablewarfarin

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Area of Science:

  • Veterinary Medicine
  • Cardiovascular Pathology

Background:

  • Aortic thrombosis (ATh) in dogs frequently arises from hypercoagulable states, though idiopathic cases occur.
  • Aortic thromboembolism (ATE) is less commonly documented than ATh.

Purpose of the Study:

  • To review the etiology, pathophysiology, and treatment strategies for aortic thrombotic disease in dogs.
  • To provide a comprehensive overview of diagnostic and therapeutic options for canine ATh and ATE.

Main Methods:

  • Diagnosis relies on recognizing varied clinical signs and utilizing imaging like ultrasound or CT for direct thrombus visualization.
  • Treatment strategies are not definitively established, but managing underlying hypercoagulable conditions is crucial.

Main Results:

  • Anticoagulant therapies, including warfarin, unfractionated heparin, and low-molecular-weight heparins, have been employed.
  • Platelet inhibitor therapy may be beneficial in conjunction with anticoagulants.

Conclusions:

  • Survival rates for dogs with ATh or ATE range from 50% to 60%.
  • Dogs presenting with chronic signs generally have a more favorable prognosis compared to acutely or severely affected dogs.