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Technical Note: scuda: A software platform for cumulative dose assessment.

Seyoun Park1, Todd McNutt1, William Plishker2

  • 1Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland 21231.

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|October 27, 2016
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Summary
This summary is machine-generated.

This study developed scuda, a software platform for accurate cumulative dose assessment in adaptive radiation therapy (ART). It efficiently tracks anatomical changes and calculates delivered radiation doses, improving treatment quality monitoring.

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Medical Imaging

Background:

  • Accurate tracking of anatomical changes and delivered radiation dose is crucial for adaptive radiation therapy (ART).
  • Efficient data management and fast processing are essential for clinical adoption of ART due to large data volumes.

Purpose of the Study:

  • To develop an accurate and efficient Software platform for CUmulative Dose Assessment (scuda).
  • To create a platform seamlessly integrated into clinical workflows for ART.

Main Methods:

  • scuda integrates deformable image registration (DIR), segmentation, dose computation, and a GUI.
  • It automatically retrieves patient data from PACS and radiotherapy informatics databases.
  • DIR uses iterative CBCT intensity correction, and dose computation is GPU-accelerated.

Main Results:

  • Validation on 30 head and neck cancer cases showed mean dose differences of 3.5 ± 5.0 Gy in parotid glands.
  • Average processing time for DIR, dose computation, and segmentation is 20 s/fraction.
  • A 35-fraction treatment, including dose accumulation, takes approximately 17 minutes.

Conclusions:

  • A unified software platform (scuda) was developed for accurate and efficient monitoring of anatomical changes and delivered dose.
  • The platform enables efficient cumulative dose computation workflows.
  • Evaluation demonstrated scuda's utility in monitoring treatment quality and detecting significant dosimetric variations in ART.