Related Experiment Video
Updated: Mar 13, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Personalized microbiome-based approaches to metabolic syndrome management and prevention
Hagit Shapiro1, Jotham Suez1, Eran Elinav1
1Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Abstract:
Personalized or precision medicine is a novel clinical approach targeted to the individual patient and based on integration of clinical, genetic, and environmental factors that define a patient uniquely from other individuals featuring similar clinical symptoms. Such a personalized medicine approach is increasingly applied for diagnosis, clinical stratification, and treatment of metabolic syndrome (MetS)-associated risks and diseases, including obesity, type 2 diabetes, non-alcoholic fatty liver disease, and their complications. One emerging factor that governs MetS manifestations is the microbiome, the composition, function, growth dynamics, associated metabolite profile and diverse effects of which on host immune and metabolic systems can all significantly affect metabolic homeostasis. Interindividual differences in microbiome composition and function, as well as personal variations in microbial-derived products, pave the way towards microbiome-based personalized medicine in treating MetS-related diseases.
Related Concept Videos
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine
Atherosclerosis III: Management
Pharmacogenomics: Identification of New Drug Targets
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Microorganisms in Medicine and Therapeutics

