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Updated: Mar 12, 2026

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
High-Valent Palladium-Promoted Formal Wagner-Meerwein Rearrangement
Hongmiao Wu1, Bin Yang1, Lin Zhu1
1Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, P. R. China.
Abstract:
An oxy-palladation, formal Wagner-Meerwein rearrangement and fluorination cascade has been established for generating fluorinated oxazolidine-2,4-diones and oxazolidin-2-ones. The reaction has a broad substrate scope in which both aryl and alkyl groups can be utilized as efficient migrating groups. Experimental evidence suggests that the reaction is initiated by anti-oxy-palladation of the olefin, followed by oxidative generation of an alkyl PdIV intermediate and a concerted migration-fluorination.
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