Myositis ossificans progressive: case report.

Area of Science:

• Genetics
• Orthopedics
• Radiology

Background:

• Myositis ossificans progressiva (MOP) is an autosomal dominant genetic disorder characterized by progressive ectopic ossification.
• It primarily affects the connective tissue of muscles, leading to skeletal malformations.

Observation:

• A 38-year-old female presented with a progressively enlarging thigh.
• Laboratory results were within normal limits.
• Radiography revealed multiple intramuscular calcifications in the right thigh.

Findings:

• The case illustrates the typical presentation of myositis ossificans progressiva.
• Diagnosis relies on clinical evaluation and radiological evidence of ectopic ossification and skeletal abnormalities.

Implications:

• Early and non-invasive diagnosis of MOP is essential.
• Accurate diagnosis guides appropriate patient management and treatment strategies.