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Published on: June 2, 2014
Gastrointestinal Headache; a Narrative Review
Majid T Noghani1, Hossein Rezaeizadeh2, Sayed Mohammad Baqer Fazljoo3
1Department of Iranian Traditional Medicine, Faculty of Medicine, Shahed University, Tehran, Iran.
Headaches may stem from gastrointestinal issues like GERD or IBS. Treating these gut disorders can often resolve associated headaches, suggesting a direct link.
Area of Science:
- Gastroenterology and Neurology
- Investigates the intricate connection between the digestive system and neurological conditions, specifically headaches.
Background:
- Primary headaches are common, but secondary headaches linked to gastrointestinal (GI) disorders are often overlooked.
- Existing research suggests a correlation between various GI conditions and primary headaches, with symptom improvement upon GI treatment.
Approach:
- Systematic literature review to gather evidence on headaches originating from the gastrointestinal system.
- Exploration of proposed pathophysiological mechanisms linking GI disorders and headaches.
Key Points:
- Associated GI disorders include dyspepsia, GERD, constipation, IBS, IBD, celiac disease, and H. pylori infection.
- Treatment of GI conditions has shown to improve or resolve associated headaches.
- Potential mechanisms include central sensitization, referred pain, serotonin pathways, and autonomic dysfunction.
Conclusions:
- A significant association exists between gastrointestinal disorders and headaches.
- Suggests the need for a distinct diagnostic category for headaches linked to treatable GI abnormalities.
- Highlights the importance of considering GI health in headache management.
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