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Updated: Mar 12, 2026

Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
ACR Appropriateness Criteria Palpable Breast Masses.
Jennifer A Harvey1, Mary C Mahoney2, Mary S Newell3
1University of Virginia Medical Center, Charlottesville, Virginia.
Imaging guidelines help characterize breast masses. Ultrasound is key for most women, with mammography for those 40+, and specific approaches for younger or pregnant patients.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Palpable breast masses are common but often present with nonspecific clinical features.
- Imaging plays a crucial role in characterizing breast masses prior to biopsy.
- Current guidelines address the appropriate use of imaging modalities for evaluating breast masses.
Purpose of the Study:
- To outline evidence-based guidelines for the appropriate use of imaging in evaluating clinically detected breast masses.
- To provide a framework for selecting the optimal imaging modality based on patient age and clinical presentation.
- To emphasize the importance of correlating imaging findings with clinical examination.
Main Methods:
- Review of current medical literature from peer-reviewed journals.
- Application of a modified Delphi consensus methodology by a multidisciplinary expert panel.
- Development of evidence-based guidelines (ACR Appropriateness Criteria®) for breast mass evaluation.
Main Results:
- Ultrasound is the primary imaging modality for most women with clinically detected breast masses.
- Diagnostic mammography is the initial choice for women aged 40 and older.
- Specific imaging recommendations vary for women under 30, pregnant/lactating women, and those aged 30-39.
- Biopsy is recommended for suspicious masses; short-term follow-up may suffice for probably benign findings like fibroadenoma.
Conclusions:
- Appropriate imaging selection is essential for accurate breast mass characterization.
- Guidelines provide a standardized approach to evaluating breast masses, improving diagnostic accuracy.
- Correlation between imaging results and clinical findings is critical for optimal patient management.
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