Related Experiment Video
Updated: Mar 12, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
Influenza: Still more important than Zika virus in 2016-2017
1Department of Infectious Diseases, Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Abstract:
Influenza kills and hospitalizes many people every year. Although the 2015-2016 influenza season was relatively mild, we should remain vigilant in our efforts to reduce the impact of future epidemics or pandemics by implementing universal influenza vaccination and early initiation of antiviral therapy for suspected cases. We don't expect influenza vaccine to prevent all cases of influenza, since immune response varies depending on age, underlying diseases, and immunosuppression.
Insights
Influenza remains a significant public health threat, causing numerous deaths and hospitalizations annually. Vigilance through universal vaccination and prompt antiviral treatment is crucial to mitigate future influenza epidemics and pandemics.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Influenza virus infections cause substantial annual morbidity and mortality worldwide.
- Despite a mild 2015-2016 season, the potential for severe epidemics and pandemics necessitates ongoing public health interventions.
Purpose of the Study:
- To emphasize the importance of continued vigilance against influenza.
- To advocate for strategies to reduce the impact of future influenza outbreaks.
Main Methods:
- This study is a review and commentary on influenza prevention strategies.
- It synthesizes existing knowledge on influenza epidemiology and control.
Main Results:
- Influenza vaccination does not guarantee complete prevention due to variable immune responses.
- Factors influencing vaccine effectiveness include age, comorbidities, and immunosuppression.
Conclusions:
- Universal influenza vaccination is recommended to reduce disease burden.
- Early antiviral therapy for suspected influenza cases is essential for prompt management.
- Continued efforts are necessary to prepare for and combat future influenza epidemics and pandemics.

