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Updated: Mar 12, 2026

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
A case of severe arthralgia with malignant mesothelioma-associated hypertrophic osteoarthropathy
Hideaki Yamakawa1, Akimasa Sekine2, Terufumi Kato2
1Department of Respiratory Medicine Kanagawa Cardiovascular and Respiratory Center Yokohama Japan; Department of Respiratory Medicine Tokyo Jikei University Hospital Tokyo Japan.
Abstract:
Hypertrophic osteoarthropathy (HOA) is a rare syndrome characterized by the abnormal proliferation of dermato-osseous tissue. We report a rare case of malignant mesothelioma-associated HOA who suffered from refractory painful osteoarthropathy. HOA can be associated with malignant mesothelioma and that may be resistant to any treatment.
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