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Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
[Pneumonia caused byCorynebacterium pseudodiphtheriticum]
Daniela Furiasse1, Ana M Gasparotto1, Aída Monterisi1
1Departamento de Bacteriología, Hospital Nacional de Clínicas, UNC, Córdoba, Argentina.
Corynebacterium pseudodiphtheriticum, normally harmless bacteria, can cause opportunistic infections like pneumonia in vulnerable patients. This case highlights successful treatment with antibiotics in an elderly patient.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Background:
- Corynebacterium pseudodiphtheriticum is typically part of the human microbiota.
- Recent decades show an increase in opportunistic infections caused by these bacteria in compromised patients.
Observation:
- A 76-year-old female with multiple comorbidities presented with pneumonia in the ICU.
- Sputum analysis revealed Gram-positive, pleomorphic rods, with C. pseudodiphtheriticum identified as the sole pathogen.
Findings:
- The patient's pneumonia was monomicrobial, caused exclusively by Corynebacterium pseudodiphtheriticum.
- Culture results confirmed C. pseudodiphtheriticum as the only bacteria present.
Implications:
- This case underscores the potential of C. pseudodiphtheriticum as an opportunistic pathogen.
- Prompt diagnosis and antibiotic treatment, such as third-generation cephalosporins, can lead to successful recovery.
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