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Cat Scratch Disease: Expanded Spectrum.

Hassan A Aziz1, Thomas P Plesec2, Camille Sabella3

  • 1Department of Ophthalmology, Cole Eye Institute, Ohio, USA.

Ocular Oncology and Pathology
|November 16, 2016
PubMed
Summary
This summary is machine-generated.

Cat scratch disease can cause rare optic nerve granulomas, mimicking retinoblastoma. Prompt treatment with antibiotics resolved the condition in a pediatric case.

Keywords:
BartonellaCat scratch diseaseHistopathologyOptic nerve granulomaPeripapillary angiomatous lesionPineal glandRetinoblastoma

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Pediatrics

Background:

  • Cat scratch disease (CSD) is a bacterial infection caused by Bartonella henselae.
  • Ophthalmic manifestations of CSD are diverse, but optic nerve involvement is uncommon.

Observation:

  • A 7-year-old boy presented with vision loss in one eye and an optic disc lesion.
  • Imaging revealed an optic nerve lesion with suspected intracranial extension and a pineal gland nodule.
  • Histopathology after enucleation confirmed granulomatous inflammation consistent with Bartonella infection.

Findings:

  • The patient was diagnosed with cat scratch disease presenting as an optic nerve granuloma.
  • The pineal gland nodule resolved after antibiotic treatment.
  • Optic nerve granulomas in CSD can be mistaken for retinoblastoma.

Implications:

  • This case expands the known spectrum of ophthalmic presentations of cat scratch disease.
  • Early recognition and treatment are crucial to prevent vision loss and misdiagnosis.
  • Bartonella infection should be considered in pediatric cases of optic nerve lesions and suspected intracranial masses.