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Updated: Mar 12, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
[Efficacy and safety of bilateral RIRS for renal lithiasis.]
José Luis Bauzá1, Enrique Pieras1, Valentí Tubau1
1Servicio de Urología. Hospital Universitari Son Espases. Palma de Mallorca. España.
Single-stage bilateral retrograde intrarenal surgery (RIRS) effectively treats bilateral kidney stones. This safe procedure achieved an 83.33% stone-free rate with minimal complications.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Nephrolithiasis Management
Background:
- Bilateral renal stones present a treatment challenge.
- Single-stage bilateral procedures aim for efficiency and reduced patient burden.
Purpose of the Study:
- To evaluate the safety and efficacy of single-stage bilateral retrograde intrarenal surgery (RIRS).
- To analyze outcomes including stone-free rate (SFR), surgical parameters, and complications.
Main Methods:
- Retrospective analysis of 24 single-stage bilateral RIRS procedures in 12 patients.
- Data collected on patient demographics, stone characteristics, operative time, and hospital stay.
Main Results:
- An 83.33% stone-free rate was achieved at 3 months post-procedure.
- Average operative time was 75 minutes, with a median hospital stay of 2 days.
- 25% of patients experienced minor complications (Clavien I-II), with no major complications.
Conclusions:
- Single-stage bilateral RIRS is a safe and effective treatment option for bilateral renal stones.
- The procedure demonstrates favorable outcomes regarding stone clearance and patient recovery.
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