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Updated: Mar 11, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
Resistant Hypertension.
Debbie Valsan1, Umber Burhan1, Geoffrey Teehan1
1Lankenau Medical Center, Lancaster Avenue, Suite 130, Wynnewood, PA, USA, 19096.
Resistant hypertension (RH) affects millions, increasing cardiovascular risks. A comprehensive strategy combining lifestyle changes, medication, and monitoring is crucial for effective blood pressure control.
Area of Science:
- Cardiology
- Nephrology
- Public Health
Background:
- Resistant hypertension (RH) affects an estimated 10 million people in the USA and is similarly prevalent globally.
- A strong linear correlation exists between hypertension and adverse cardiovascular outcomes, underscoring the need for improved blood pressure management.
Purpose of the Study:
- To advocate for a multi-pronged approach to managing resistant hypertension.
- To highlight the limitations of solely pharmacologic interventions.
Main Methods:
- Emphasizing lifestyle modifications, including reduced sodium intake and adherence to diets like DASH (Dietary Approaches to Stop Hypertension).
- Advising avoidance of blood pressure-elevating agents such as non-steroidal anti-inflammatory drugs (NSAIDs).
- Recommending frequent follow-up for treatment optimization and home blood pressure monitoring.
Main Results:
- A multi-faceted strategy is essential for effective RH management.
- Lifestyle interventions and medication adjustments are key components.
- Home blood pressure monitoring facilitates better control.
Conclusions:
- Effective management of resistant hypertension requires a comprehensive approach beyond pharmacologic therapy alone.
- Integrating lifestyle changes, judicious medication use, and regular monitoring improves patient outcomes.
- Future therapeutic strategies may involve device-based interventions.
Related Concept Videos
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension and Regulation of Blood Pressure
Hypertension III: Clinical Manifestations and Diagnostic Studies
Antihypertensive Drugs: Angiotensin II Receptor Blockers
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

