A comprehensive database of published tDCS clinical trials (2005-2016)

Area of Science:

• Neuroscience
• Neurology
• Psychiatry

Background:

• Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique.
• Clinical applications of tDCS began in March 2005.
• tDCS has shown potential for modifying brain functions.

Purpose of the Study:

• To compile a comprehensive list of 340 articles assessing the clinical effects of tDCS in patients.
• To provide a detailed overview of raw data from tDCS studies.
• To serve as a resource for researchers in the field of tDCS.

Main Methods:

• Systematic review of 340 articles (excluding case reports) on tDCS clinical effects.
• Focus on studies involving cortical stimulation targets.
• Data collected included clinical condition, study design, sample size, stimulation parameters, session details, and outcomes.

Main Results:

• The review covers a wide range of conditions including pain, Parkinson's disease, stroke, epilepsy, dementia, depression, schizophrenia, and autism.
• Detailed data on study parameters and clinical outcomes are presented for each condition.
• The article provides a raw data overview, not a meta-analysis.

Conclusions:

• This compilation offers a broad overview of the clinical research landscape for tDCS.
• The data presented can guide future research and clinical application of tDCS.
• Researchers can use this resource to understand the current state of tDCS evidence across diverse conditions.