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Updated: Mar 11, 2026

Hyperpolarized Xenon for NMR and MRI Applications
Published on: September 6, 2012
Remote detection of hyperpolarized 129Xe resonances via multiple distant dipolar field interactions with 1H
Le Zhang1, Michael Antonacci2, Alex Burant2
1Department of Applied Physical Sciences, UNC-Chapel Hill, Chapel Hill, North Carolina 27599, USA.
Abstract:
A remote detection scheme utilizing the distant dipolar field interaction between two different spin species was proposed by Granwehr et al. [J. Magn. Reson. 176(2), 125 (2005)]. In that sequence 1H spins were detected indirectly via their dipolar field interaction with 129Xe spins, which served as the sensing spins. Here we propose a modification of the proposed detection scheme that takes advantage of the longer T1 relaxation time of xenon to create a long lasting dipolar field with which the fast relaxing 1H spins are allowed to interact many times during a single acquisition. This new acquisition scheme improves detection sensitivity, but it also presents some challenges.
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