Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.0K
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

85
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
85
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

681
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
681
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.4K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.4K
Infection01:20

Infection

13.8K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
13.8K
Hypersensitivity Reactions: Immune-Complex Reactions01:19

Hypersensitivity Reactions: Immune-Complex Reactions

81
Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum...
81

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relationship Between Post-traumatic Stress Symptoms and Anticipatory Grief in Family Caregivers of Patients With Advanced Lung Cancer: The Mediation Role of Illness Uncertainty.

Frontiers in psychiatry·2022
Same author

Attenuated Duck Hepatitis A Virus Infection Is Associated With High mRNA Maintenance in Duckling Liver <i>via</i> m6A Modification.

Frontiers in immunology·2022
Same author

Duck hepatitis A virus type 1 mediates cell cycle arrest in the S phase.

Virology journal·2022
Same author

Functions of Viroporins in the Viral Life Cycle and Their Regulation of Host Cell Responses.

Frontiers in immunology·2022
Same author

Features and Functions of the Conserved Herpesvirus Tegument Protein UL11 and Its Binding Partners.

Frontiers in microbiology·2022
Same author

The autophagy-related degradation of MDA5 by Tembusu virus nonstructural 2B disrupts IFNβ production.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2022

Related Experiment Video

Updated: Mar 11, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.7K

Infectious Complications in Atopic Dermatitis.

Di Sun1, Peck Y Ong2

  • 1Department of Pediatrics, Keck School of Medicine, University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA.

Immunology and Allergy Clinics of North America
|November 26, 2016
PubMed
Summary

Atopic dermatitis involves skin barrier, immune, and microbiome issues, increasing infection risk. Prevention requires maintaining skin integrity, managing flares, and addressing pathogens.

Keywords:
Atopic dermatitisEczema herpeticumInnateKeratinocytesStaphylococcal aureus

More Related Videos

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

5.2K

Related Experiment Videos

Last Updated: Mar 11, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.7K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

5.2K

Area of Science:

  • Dermatology
  • Immunology
  • Microbiology

Background:

  • Atopic dermatitis (AD) is a chronic inflammatory skin condition.
  • AD involves a compromised skin barrier, immune dysregulation, and altered skin microbiome.
  • These factors predispose individuals to secondary infections.

Purpose of the Study:

  • To review the pathogenesis of atopic dermatitis.
  • To elucidate the mechanisms of infectious complications in AD patients.
  • To discuss strategies for preventing secondary infections.

Main Methods:

  • Literature review of pathogenesis and infectious mechanisms in atopic dermatitis.
  • Analysis of bacterial, viral, and fungal infections associated with AD.
  • Synthesis of current approaches to infection prevention.

Main Results:

  • Atopic dermatitis pathogenesis involves complex interactions between skin barrier defects, immune responses, and the skin microbiome.
  • Patients with atopic dermatitis are susceptible to infections caused by various pathogens.
  • Acute management of infections is possible, but long-term prevention is crucial.

Conclusions:

  • Secondary infections are a significant concern in atopic dermatitis management.
  • Prevention strategies must address skin barrier function, inflammation control, and pathogen burden.
  • A multipronged approach is essential for preventing and managing infectious complications in AD.