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Medication Adherence Pattern and Factors affecting Adherence in Helicobacter Pylori Eradication Therapy
S Shakya Shrestha1, M Bhandari2, S R Thapa2
1Department of Pharmacology, School of Medical Sciences, Kathmandu University. Research and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Kavre, Nepal.
Kathmandu University Medical Journal (KUMJ)
|November 29, 2016
Summary
Most patients with Helicobacter pylori (H. pylori) infection adhere to their medication. Forgetfulness is the primary reason for missed doses among non-adherent individuals, impacting treatment success.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Pharmacology
Background:
- Helicobacter pylori (H. pylori) infection affects nearly half the global population, necessitating effective treatment strategies.
- Optimizing H. pylori eradication rates hinges on high patient adherence to complex multi-drug therapies.
- Understanding factors influencing medication adherence is crucial for successful H. pylori treatment outcomes.
Purpose of the Study:
- To investigate medication adherence patterns in patients diagnosed with H. pylori infection.
- To identify key factors associated with non-adherence to prescribed H. pylori eradication therapies.
Main Methods:
- A study was conducted on H. pylori positive patients undergoing eradication therapy.
- Data was collected via interviews using a structured questionnaire after obtaining informed consent.
- Statistical analysis was performed using SPSS, with a p-value < 0.05 considered significant.
Main Results:
- Out of 70 participants, 85.7% demonstrated adherence to their medication regimen.
- Forgetfulness was cited as the main reason for missed doses by 80% of non-adherent patients.
- Adherence showed a significant association with the absence of symptomatic relief (p<0.05), but not with gender, age, or literacy.
Conclusions:
- The majority of patients with H. pylori infection exhibit good medication adherence.
- Forgetfulness is the predominant factor contributing to missed doses in non-adherent patients.
- Addressing forgetfulness may improve adherence and treatment efficacy for H. pylori infections.
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