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Smartphone-based portable wireless optical system for the detection of target analytes
Shreedhar Gautam1, Bhagwan S Batule1, Hyo Yong Kim1
1Department of Chemical and Biomolecular Engineering (BK 21+ program), Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Biotechnology Journal
|December 2, 2016
Summary
A new smartphone-based system, the Portable and Wireless Optical System (PAWS), enables rapid, on-site detection of hazardous molecules. This nanobiotechnology innovation offers a wireless solution for quantitative analysis in diverse applications.
Area of Science:
- Nanobiotechnology
- Biosensing
- Optical detection
Background:
- On-site wireless measurement of hazardous molecules and biomarkers presents significant challenges.
- Existing methods often lack the speed, accuracy, or portability required for real-time analysis.
Purpose of the Study:
- To develop a novel smartphone-based Portable and Wireless Optical System (PAWS) for rapid, quantitative, and on-site analysis.
- To demonstrate the feasibility of PAWS using gold nanoparticles and horse radish peroxidase for detecting model analytes.
Main Methods:
- Utilized gold nanoparticles (GNP) and horse radish peroxidase (HRP) for colorimetric signal generation.
- Integrated a colorimetric-to-electrical signal conversion within the device.
- Employed smartphone wireless communication for data acquisition and analysis.
Main Results:
- Successfully detected two model target molecules, melamine and hydrogen peroxide, using the PAWS device.
- Demonstrated wireless transmission and processing of analytical data via a smartphone.
- Achieved quantitative measurement of analyte concentrations and their significance.
Conclusions:
- The PAWS device offers a programmable and miniaturized platform for rapid, on-site detection.
- This technology holds significant potential for point-of-care testing (POCT) applications.
- PAWS facilitates efficient analysis of various analytes in real-world settings.
