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A Comparative Analysis of Goldmann Tonometry Correction
Magdalena Asejczyk-Widlicka1, Wieslaw Srodka, Barbara K Pierscionek
1*Department of Optics and Photonics †Deformable Body Mechanics Faculty Unit, Wroclaw University of Technology, Smoluchowskiego, Wroclaw, Poland ‡School of Life Sciences, Faculty of Science, Engineering and Computing, Kingston University London, UK.
Correction formulas for Goldmann applanation tonometry (GAT) show varying accuracy in primary open-angle glaucoma patients. The best formula depends on intraocular pressure (IOP) levels, with specific models performing better at different IOP ranges.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Optometry
Background:
- Intraocular pressure (IOP) measurement using Goldmann applanation tonometry (GAT) relies on assumptions about corneal properties.
- Variations in corneal curvature and thickness can affect GAT accuracy.
- Several correction formulas have been developed to account for corneal biomechanics.
Purpose of the Study:
- To evaluate the in vivo accuracy of different IOP correction formulas in primary open-angle glaucoma (POAG) patients.
- To compare corrected GAT IOP measurements with those from Pascal dynamic contour tonometry (DCT).
- To identify the most accurate correction formula based on IOP levels.
Main Methods:
- 108 POAG participants (39-81 years) underwent ophthalmologic examinations.
- IOP was measured using both GAT and DCT.
- Six different GAT correction formulas were applied.
- Results were analyzed and compared between GAT (corrected) and DCT measurements.
Main Results:
- For IOP values up to 29 mm Hg, two formulas demonstrated minimal and similar mean differences and standard deviations compared to DCT.
- For IOP values of 30 mm Hg and above, a formula incorporating corneal buckling showed the closest agreement with DCT measurements.
- Formula performance varied significantly depending on the IOP range.
Conclusions:
- The accuracy of IOP correction formulas in POAG is variable.
- The choice of the most appropriate correction formula is dependent on the measured IOP.
- Dynamic contour tonometry offers a corneal-independent method for IOP assessment.
