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Effects of Anti-CD206 Antibodies on Macrophage Functions in Male CBF1 Mice with Lipidemia
A P Lykov1, T A Korolenko2, L V Sakhno3
1Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia. aplykov2@mail.ru.
Bulletin of Experimental Biology and Medicine
|December 3, 2016
Abstract:
The effects of anti-CD208 antibodies (mannose receptor) on functional characteristics of peritoneal macrophages were studied in intact mice and mice with lipidemia induced by poloxamer-407. Lipidemia was associated with suppression of phagocytosis and increase in spontaneous proliferative potential and NO production by macrophages. Anti-CD206 antibodies suppressed NO production by macrophages in mice with lipidemia.
