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Updated: Mar 11, 2026
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Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
Published on: October 20, 2011
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Endodontic Microbiology and Pathobiology: Current State of Knowledge
1Department of Endodontics, School of Dentistry, University of North Carolina at Chapel Hill, 1098 First Dental Building, CB# 7450, Chapel Hill, NC 27599-7450, USA.
Dental Clinics of North America
|December 4, 2016
Summary
Recent innovations allow novel exploration of endodontic diseases. Advanced tools identify numerous microorganisms and host response factors, paving the way for future endodontic research and treatments.
Area of Science:
- Endodontics
- Microbiology
- Immunology
Background:
- Endodontic diseases affect pulp and periapical tissues.
- Traditional methods have limitations in understanding complex microbial communities and host responses.
Purpose of the Study:
- To review recent advancements in endodontic microbiology and host response.
- To highlight the impact of new research tools on endodontic disease exploration.
- To discuss future innovative directions in the field.
Main Methods:
- Review of current literature on endodontic microbiology and host response.
- Focus on innovative research tools such as next-generation sequencing, bioinformatics, and genome-wide association studies.
Main Results:
- Identification of hundreds of microorganisms involved in endodontic infections.
- Characterization of various host response factors contributing to disease pathogenesis.
- Demonstration of how advanced technologies enable deeper insights into endodontic diseases.
Conclusions:
- Novel research tools have significantly advanced our understanding of endodontic microbiology and host response.
- Continued innovation in research methodologies promises further breakthroughs in diagnosing and treating endodontic diseases.
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