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Updated: Mar 11, 2026
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Neoadjuvant and Adjuvant Therapy for Non-Small Cell Lung Cancer
Jody C Chuang1, Ying Liang2, Heather A Wakelee3
1Divisions of Hematology and Oncology, Department of Medicine, Stanford Hospital and Clinics, 875 Blake Wilbur Drive, Stanford, CA 94305, USA.
Abstract:
The use of 4 cycles of cisplatin-based adjuvant chemotherapy is now the standard of care for patients with resected stage II and IIIA non-small cell lung cancer. Neoadjuvant chemotherapy lacks the same level of data as adjuvant treatment, but meta-analyses of this approach support its use. Selection of patients who are most likely to benefit from chemotherapy remain elusive. Ongoing adjuvant trials are exploring biomarkers, molecularly targeted agents, postoperative radiation therapy, and immunotherapy.
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