Related Experiment Video
Updated: Mar 10, 2026
10:19
Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project
Published on: April 8, 2017
18.2K
Snake Genome Sequencing: Results and Future Prospects
Harald M I Kerkkamp1, R Manjunatha Kini2, Alexey S Pospelov3
1Institute of Biology, University of Leiden, Leiden 2300 RA, The Netherlands. h.m.i.kerkkamp@biology.leidenuniv.nl.
Toxins
|December 6, 2016
Summary
Snake genome sequencing is advancing, offering insights into evolution and toxinology. Future genomic studies will aid in developing antivenoms and understanding toxin gene regulation.
Area of Science:
- Genomics
- Toxinology
- Evolutionary Biology
Background:
- Snake genome sequencing is nascent compared to other species.
- Limited draft genomes are available for snakes.
- Existing snake genomes offer initial biological insights.
Purpose of the Study:
- To review current snake genome projects.
- To discuss findings from published snake genomes, focusing on toxinology.
- To explore the future of snake genomics.
Main Methods:
- Overview of ongoing snake genome projects.
- Analysis of biological findings from published draft snake genomes.
- Discussion of challenges and future directions in snake genomics.
Main Results:
- Early snake genomes provide foundational data for biological research.
- Emphasis on toxinology reveals insights into venom evolution and composition.
- Repetitive sequences pose assembly challenges, but new technologies offer solutions.
Conclusions:
- Snake genomics is a developing field with significant potential.
- Advancements in sequencing technologies will facilitate genome assembly.
- Snake genomes are crucial for understanding toxin gene organization, developing antivenoms, and studying gene expression.
Related Concept Videos
03:00Next-generation Sequencing
100.1K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
100.1K
02:02Genomics
41.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.3K
01:57Sanger Sequencing
777.0K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
777.0K
02:54Evolutionary Relationships through Genome Comparisons
7.1K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.1K
03:36Genome Annotation and Assembly
21.3K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
21.3K
01:05Maxam-Gilbert Sequencing
13.4K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
Challenges of the Maxam-Gilbert Method
The...
13.4K