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Updated: Mar 10, 2026

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position
Published on: August 17, 2017
Low-energy trauma-induced intercondylar femoral fracture
Mathias Aeby1, Tobias Wyss2, Birgit Mentrup3
1Department of Rheumatology, Immunology and Allergology, Inselspital Bern, Bern, Switzerland.
Abstract:
We present a 44-year-old female patient with recurrent fragility fractures including an intercondylar femoral fracture and with normal planar bone densitometry. Diagnosis of hypophosphatasia was suggested by low volumetric cortical bone mineral density and laboratory findings. DNA sequencing revealed heterozygous mutations in the exons 5, 6 and 9 of the ALPL gene, thus confirming the suspected diagnosis.
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