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Anaphylaxis to peanuts: clinical correlation to skin tests
J N Kalliel1, D E Klein, G A Settipane
1Program in Medicine, Brown University, Providence, RI.
Allergy Proceedings : the Official Journal of Regional and State Allergy Societies
|July 1, 1989
Summary
This study found that 3.2% of atopic patients evaluated for allergies showed a positive skin test to peanuts. Of those with positive skin tests, over 60% demonstrated clinical peanut sensitivity.
Area of Science:
- Allergy and Immunology
- Clinical Research
Background:
- Routine allergy evaluations often include testing for various environmental allergens.
- Peanut sensitivity is a common concern among patients seeking allergy assessment.
Purpose of the Study:
- To ascertain the prevalence of peanut sensitivity in patients undergoing standard allergy testing.
- To correlate skin test results with clinical history and challenge outcomes for peanut allergy.
Main Methods:
- Skin prick testing was performed on 365 consecutive patients using a panel of allergens, including peanut extract.
- Atopic status was determined, and patients with positive peanut skin tests underwent further evaluation, including open challenge if indicated.
Main Results:
- Eight out of 248 atopic patients (3.2%) exhibited a positive skin test to peanut extract.
- Four of these eight patients reported a history consistent with peanut sensitivity.
- One patient, asymptomatic by history, reacted positively to an open peanut challenge, confirming clinical sensitivity.
Conclusions:
- A notable percentage of atopic individuals referred for allergy evaluation exhibit peanut sensitivity.
- Skin testing is a valuable tool for identifying potential peanut allergy, but clinical correlation and challenge may be necessary for definitive diagnosis.