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Structural dynamics and DNA interaction of human TFIID

Eva Nogales1,2,3, Jie Fang2, Robert K Louder4

  • 1a Molecular and Cell Biology Department and QB3 Institute , UC Berkeley , CA , USA.

Transcription
|December 10, 2016
PubMed
Summary

The TFIID complex, crucial for gene transcription, exhibits significant conformational flexibility. This plasticity allows it to recognize diverse DNA promoter elements and adapt its binding affinity, aiding gene regulation.

Keywords:
conformational heterogeneitycryo-EMpre-initiation complextranscription initiation

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