[Three Years Follow-up Study after Refractive Small Incision Lenticule Extraction (SMILE) Using 500 kHz Femtosecond...

Area of Science:

• Ophthalmology
• Refractive Surgery
• Laser Vision Correction

Background:

• Assessing long-term outcomes of ReLEx SMILE laser settings.
• Evaluating efficacy in unselected patients with moderate to high myopia.
• Real-world clinical trial data collection over three years.

Purpose of the Study:

• To evaluate the 3-year clinical results of ReLEx SMILE.
• To analyze outcomes based on myopia severity (moderate vs. high).
• To assess the stability and safety of the procedure.

Main Methods:

• Prospective clinical trial involving 50 eyes from 27 patients.
• Utilized VisuMax femtosecond laser in 'fast mode'.
• Categorized patients into moderate myopia subgroup (preoperative < -6D).

Main Results:

• Spherical equivalent improved from -6.18 D to -0.18 D overall.
• Moderate myopia subgroup achieved -0.04 D SE.
• 14% gained one line, 22% lost one line of CDVA; minimal regression observed.
• No late adverse events reported; undercorrection noted for myopia > -6.0D.

Conclusions:

• ReLEx SMILE demonstrates significant stability for various myopia levels after 3 years.
• Primary undercorrection is prevalent in eyes with myopia exceeding -6.0D.
• Nomogram adjustments are recommended for higher myopia cases to optimize outcomes.