Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relationship between muscle FNDC5, FGF21 mRNA, miR-150 and bone loss after sciatic denervation.

Journal of physiology and biochemistry·2026
Same author

Sensing with (One or Many) Upconverting Nanoparticles.

Accounts of chemical research·2026
Same author

TXRF Spectrometry for Investigating CaF<sub>2</sub>:Nd<sup>3+</sup>,Y<sup>3+</sup> Nanoparticle Diffusion in Tumoral Cancer 3D Spheroids.

International journal of molecular sciences·2026
Same author

Upconversion particle-based optical tweezers for sensing applications.

Nature protocols·2026
Same author

Tunable optical matter: electrostatic repulsion modulates near- and far-field gold nanoparticle arrangements.

Nanoscale advances·2026
Same author

Accurate and Fast Thermal Sensing via Phase-Responsive Nanothermometers and Neural Networks.

Nano letters·2025
Same journal

Spider-Silk-Like Single-Fiber Actuators with Two Actuation Modes Driven by Water.

Nano letters·2026
Same journal

Clicking 1,4-Dithiin Conjugated Dimaleimides for Chiroptical Evolution and Nanofabrication.

Nano letters·2026
Same journal

Dynamic Quantum Gate Based on Controllable Chiral Liquid Crystal Nanostructure.

Nano letters·2026
Same journal

Activating Phase-Transition Toughening in van der Waals Semiconductor GaTe.

Nano letters·2026
Same journal

Dual-Mode Nucleation and Dynamic Alloying of Silicon on Ag(111).

Nano letters·2026
Same journal

Surface-Neutralized HgCdSe Quantum Dots for High-Detectivity Infrared Photodetectors.

Nano letters·2026
See all related articles

Related Experiment Video

Updated: Mar 10, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

5.8K

Optical Torques on Upconverting Particles for Intracellular Microrheometry.

Paloma Rodríguez-Sevilla1, Yuhai Zhang2, Nuno de Sousa3,4

  • 1Fluorescence Imaging Group, Departamento de Física de Materiales, Universidad Autónoma de Madrid , 28049 Madrid, Spain.

Nano Letters
|December 15, 2016
PubMed
Summary
This summary is machine-generated.

Controlling the orientation of upconverting particles is key for their use as bioprobes. This study shows how optical traps can orient these particles and measure medium viscosity.

Keywords:
Optical trappingfinite element methodmicrorheometryoptical torqueupconverting particleviscosity

More Related Videos

Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System
09:48

Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

Published on: June 30, 2018

9.4K
Label-free Single Molecule Detection Using Microtoroid Optical Resonators
08:53

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

10.0K

Related Experiment Videos

Last Updated: Mar 10, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

5.8K
Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System
09:48

Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

Published on: June 30, 2018

9.4K
Label-free Single Molecule Detection Using Microtoroid Optical Resonators
08:53

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

10.0K

Area of Science:

  • Nanotechnology
  • Biophysics
  • Spectroscopy

Background:

  • Controlling particle orientation is crucial for advanced applications.
  • Upconverting particles offer unique properties as multifunctional bioprobes.

Purpose of the Study:

  • To investigate the orientation dynamics of single upconverting particles in optical traps.
  • To demonstrate the use of these dynamics for determining medium properties.

Main Methods:

  • Time-resolved, single-particle polarized spectroscopy.
  • Optical trapping techniques.
  • Numerical simulations and calculations of dipole magnetic interactions.

Main Results:

  • A unique stable orientation configuration for upconverting particles was identified.
  • Optical torques, driven by dipole magnetic interactions, were found to be responsible for orientation.
  • The method successfully determined intracellular dynamic viscosity.

Conclusions:

  • Single-particle polarized spectroscopy in optical traps provides precise control and orientation analysis of upconverting particles.
  • This technique offers a novel approach for probing the properties of complex media, including intracellular environments.